Chris Horton

When away from the wards, I enjoy engaging in teaching at all levels across the medical course. Currently, I provide Physiology and Pharmacology tutorials to first-year medical students at Trinity, covering topics in gross human anatomy and embryology. As a Fellow in Anatomy, I provide demonstration room seminars to first- and third-year medical students and have recently produced three textbooks entitled The Principles of Clinical Anatomy with Mr Tom Cosker and Professor John Morris, for the use of Oxford medical students. I have recently completed my Postgraduate Certificate in Teaching and Learning in Higher Education in Oxford and obtained Fellowship of the Higher Education Academy (FHEA). I also provide regular training in Advanced Life Support (ALS) to clinicians as a course instructor.  

I completed my BM BCh degree in 2019, having completed my pre-clinical years and undergraduate degree in Medical Sciences at Trinity. I now work as Core Surgical Trainee in South East London, and regularly return to Oxford during term-time to provide undergraduate teaching. 

For much of my time in Oxford, I have been actively involved in both basic science and clinical research. I have recently carried out projects with interventional radiologists, orthopaedic surgeons and spinal surgeons, and have presented my work at National Conferences. During my undergraduate studies at Trinity College, I worked under Professor Paul Fairchild, at the Sir William Dunn School of Pathology, developing novel methods to generate immunogenic and tolerogenic dendritic cells from induced pluripotent stem cells. This work has allowed us to create a theoretically infinite supply of functional, adult-phenotype antigen presenting cells, which can be used in cancer immunotherapy and transplant tolerance research.

Leung, B., Williams, M., Horton, C. and Cosker, T, ‘Modernising Anatomy Teaching: Which Resources Do Students Rely On?’ Journal of Medical Education and Curricular Development 2020  

Carroll, L., Braeutigam, S., Dawes, J., Krsnik, Z., Kostovic, I., Coutinho, E., Dewing, J., Horton, C., Gomez-Nicola, D. and Menassa, D, ‘Autism Spectrum Disorders: Multiple Routes to, and Multiple Consequences of, Abnormal Synaptic Function and Connectivity’, The Neuroscientist 2020  

Whiles, E., Shafafy, R., Valsamis, E., Horton, C., Morassi, G., Stokes, O. & Elsayed, S., ‘The Management of Symptomatic Lumbar Disc Herniation in Pregnancy: A Systematic Review’, Global Spine Journal December 2019  

Horton, C., Davies, T., Lahiri, P., Sachamitr, P. & Fairchild, P., ‘iPS cells reprogrammed from primary dendritic cells provide an abundant source of immunostimulatory dendritic cells for use in immunotherapy’, Stem Cells 2019 38, 67-79 

Fairchild, P., Davies, T., Horton, C., Shanmugarajah, K. & Bravo, M., ‘Immunotherapy with iPSC-derived dendritic cells brings a new perspective to an old debate: autologous versus allogeneic?’, Cell & Gene Therapy Insights 2019; 5(5), 565–566. 

Horton C, Shanmugarajah K, Fairchild PJ., ‘Harnessing the properties of dendritic cells in the pursuit of immunological tolerance’, Biomedical Journal 2017 40, 80–93 

Fairchild, P., Horton, C., Lahiri, P., Shanmugarajah, K. & Davies, T., ‘Beneath the sword of Damocles: regenerative medicine and the shadow of immunogenicity’, Regenerative Medicine 11 (2016), 817-829